副研究员
招生学科专业：
控制科学与工程 -- 【招收硕士研究生】 -- 自动化学院
电子信息 -- 【招收硕士研究生】 -- 自动化学院
电子信息 -- 【招收硕士研究生】 -- 计算机科学与技术学院
学历：南京航空航天大学
学位：工程硕士专业学位
所在单位：无人机研究院
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所属单位：航空学院
发表刊物：Ultrasound Med. Biol.
摘要：The manipulation of motile and still single cells with the simultaneous features of selective trapping, 3-D path free transport, position-controllable release and little heat damage has been a significant challenge. We developed an ultrasonic method for capturing motile and still single cells with the aforementioned features in a droplet. During manipulation, a micromanipulation probe (MMP), which vibrated linearly with a trajectory parallel to a silicon substrate, was immersed in the droplet and was not in contact with the substrate. Motile and still single cells, such as Chattonella marina with a length of 30–50 μm and yeast cells with a diameter of 3–10 μm, at the interface between the droplet and substrate were selectively sucked onto the vibrating MMP and transported via a 3-D route inside the droplet by moving the MMP (or the device). The MMP and captured single cells were in contact, making the release position controllable. The measured temperature rise of the MMP was <0.1°C; thus, it is competitive for the manipulation of biological samples. Finite-element analyses revealed that the contact-type capture was due to acoustic radiation force generated by the ultrasonic field around the vibrating MMP. The dependence of the capture capability and working frequency bandwidth on the working conditions was investigated experimentally. © 2019 World Federation for Ultrasound in Medicine & Biology
ISSN号：0301-5629
是否译文：否
发表时间：2019-11-01
合写作者：Liu, Qingyang,胡俊辉,Minin, Igor V.,Minin, Oleg V.
通讯作者：杨柳庆,胡俊辉
