点击次数：

所属单位：材料科学与技术学院

发表刊物：CURRENT PHARMACEUTICAL DESIGN

关键字：Antibacterial biomaterials biological glass graphene graphene oxide anti-infective properties

摘要：Infections caused by microbial proliferation are one of the common issues and serious threats to the medical care, and they usually result in disease spread. Therefore, it is a significant issue for developing the antiinfective biomaterials to control this problem, according to the specific clinical application. Meanwhile, all their properties, the best anti-infective performance, the safe biocompatibility and the appropriate tissue interactions must be conformed to each other. At present, technologies are developing novel biomaterials and surfaces endowed with anti-infective properties, relying either on bactericidal or anti-biofilm activities. This review focuses on thoroughly summarizing numerous kinds of antibacterial biomaterials, including the antibacterial matrix biomaterials, antibacterial coatings and films, nanostructured materials and antibacterial fibers. Among these strategies, the utilization of bio-glass base and graphene base antibacterial matrix, and their effects on the antibiosis mechanism were emphatically discussed. Simultaneously, the effects and mechanisms of nano-coated metallic ions are also mentioned. Overall, there is a wealth of technical solutions to contrast the establishment of an implant infection. The lack of well-structured prospective multicenter clinical trials hinders the achievement of conclusive data on the efficacy and comparative performance of antibacterial biomaterials.

ISSN号：1381-6128

是否译文：否

发表时间：2018-01-01

合写作者：Xu, Tengzhou,Chen, Zhou,Fan, Yuxin,Mao, Haifeng

通讯作者：Chen, Zhou,陈照峰